Dr. Oliver Wolf reluctantly accepts a job at Bronx General Hospital where he's forced to work with a team of interns as they treat a mother who can no longer recognize her kids.

When a high school girls’ basketball coach is faced with a debilitating illness, Dr. Wolf must help his patient reconnect with her body before it’s too late.

A member of a biker gang seeks out Wolf's help as he grapples with life-threatening memory loss.

When a bloody bride stumbles into Bronx General, Wolf goes to extreme measures in a race against the clock to save her and her missing husband.

Wolf must help a Marine grapple with mysterious symptoms before the birth of his child.

Dr. Wolf and the interns go back to high school to treat a group of pregnant teenagers.

Dr. Wolf and the team perform their most experimental treatment yet: a brain computer interface implantation in their John Doe patient's brain.

When an elderly woman is brought in with signs of dementia, Dr. Wolf investigates whether she's suffering from a neurological disorder or having a late-in-life awakening.

When an artist refuses to paint for his upcoming show, Dr. Wolf and his team must figure out why. Dr. Pierce goes into uncharted territory with a patient.

An unexpected patient crashes into Bronx General with mysterious life-threatening symptoms.

Dr. Pierce treats a patient in crisis, presenting an ethical dilemma. Dr. Wolf and Dr. Nichols disagree on how to treat a patient.

Dr. Wolf and his team face their biggest challenge yet when an apartment building collapses in the Bronx.

Dr. Wolf meets a pastor dealing with mysterious visions. The interns grapple with the fallout from the building collapse.

Dr. Wolf helps an MMA fighter with mysterious symptoms. Dr. Pierce considers a career outside of Bronx General.

A reality show contestant lands at the hospital with an unusual delusion. Dr. Pierce fights for her future at Bronx General.

Dr. Wolf and his team treat a young patient accused of a serious crime.

Dr. Wolf and Dr. Pierce are tasked with a house call to evaluate a woman under a conservatorship. Dr. Kinney's curiosity is piqued by a patient outside the hospital.

When two patients arrive in critical condition, Dr. Wolf and Dr. Nichols must do whatever it takes to keep them alive.

Dr. Wolf is haunted by a ghost from his past. A patient arrives at Bronx General who appears to have risen from the dead.

A blast from the past shakes up Dr. Wolf's world when he becomes his next patient.

On a flight gone wrong, one patient’s life is quite literally turned upside down.

Dr. Wolf helps a firefighter and his family navigate a life-changing diagnosis on Thanksgiving.

Dr. Wolf helps a ballerina recover after a mystery illness. The team tries to save Sam's life and get him on the transplant list.

Dr. Wolf and the team come together as one of their own fights for their life.